Pharmaceutical Cleanroom Cleaning Checklist

This checklist standardizes pharmaceutical cleanroom cleaning checklist using ISSA-aligned methods and OSHA documentation requirements. Use it daily to verify high-touch disinfection, floor care, restroom hygiene, waste handling, and chemical safety. Record findings and capture sign-off to support audits and client SLAs.

  • Industry: Cleaning & Janitorial
  • Frequency: Daily
  • Estimated Time: 5-10 minutes
  • Role: Plant Operations Lead
  • Total Items: 35
  • Compliance: OSHA 29 CFR 1910.1200 (Hazard Communication), OSHA 29 CFR 1910.132 (PPE), OSHA 29 CFR 1910.141 (Sanitation)

Pre-Service Setup & Site Readiness

Confirm supplies, access, and safety controls before starting work.

  • Pre-Service Setup tasks completed per SOP?
  • Any issues found that require escalation?
  • Area secured and signage/cones placed as needed?
  • Time spent in this section
  • SDS available and chemical labels readable (GHS)?

High-Touch Surfaces

Disinfect high-frequency touchpoints using approved disinfectants and dwell times.

  • High-Touch Surfaces tasks completed per SOP?
  • Any issues found that require escalation?
  • Area secured and signage/cones placed as needed?
  • Time spent in this section
  • Notes

Floors & Surfaces

Vacuum, mop, and maintain floors per surface type and traffic conditions.

  • Floors tasks completed per SOP?
  • Any issues found that require escalation?
  • Area secured and signage/cones placed as needed?
  • Consumables restocked to minimum par level?
  • Notes

Restrooms & Hygiene Areas

Clean and restock hygiene areas; verify odors, fixtures, and consumables.

  • Restrooms tasks completed per SOP?
  • Any issues found that require escalation?
  • Area secured and signage/cones placed as needed?
  • Consumables restocked to minimum par level?
  • Notes

Waste, Linen & Material Handling

Handle waste and linen safely to prevent cross-contamination and injuries.

  • Waste, Linen tasks completed per SOP?
  • Any issues found that require escalation?
  • Area secured and signage/cones placed as needed?
  • Time spent in this section
  • Photo evidence (waste staging / dumpster area)

Chemicals, PPE & Documentation

Verify SDS, dilution ratios, labeling, PPE use, and documentation for compliance.

  • Chemicals, PPE tasks completed per SOP?
  • Any issues found that require escalation?
  • Area secured and signage/cones placed as needed?
  • Time spent in this section
  • SDS available and chemical labels readable (GHS)?

QA & Sign-Off

Verify quality, resolve misses, and capture sign-off for accountability.

  • QA walkthrough completed with client/site lead?
  • Rework required before sign-off?
  • Client satisfaction rating
  • Supervisor/Lead Signature
  • Client/On-site Contact Signature

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Why Use This Pharmaceutical Cleanroom Cleaning Checklist?

This pharmaceutical cleanroom cleaning checklist helps cleaning & janitorial teams maintain compliance and operational excellence. Designed for plant operations lead professionals, this checklist covers 35 critical inspection points across 7 sections. Recommended frequency: daily.

Ensures compliance with OSHA 29 CFR 1910.1200 (Hazard Communication), OSHA 29 CFR 1910.132 (PPE), OSHA 29 CFR 1910.141 (Sanitation). Regulatory-aligned for audit readiness and inspection documentation.

Frequently Asked Questions

What does the Pharmaceutical Cleanroom Cleaning Checklist cover?

This checklist covers 35 inspection items across 7 sections: Pre-Service Setup & Site Readiness, High-Touch Surfaces, Floors & Surfaces, Restrooms & Hygiene Areas, Waste, Linen & Material Handling, Chemicals, PPE & Documentation, QA & Sign-Off. It is designed for cleaning & janitorial operations and compliance.

How often should this checklist be completed?

This checklist should be completed daily. Each completion takes approximately 5-10 minutes.

Who should use this Pharmaceutical Cleanroom Cleaning Checklist?

This checklist is designed for Plant Operations Lead professionals in the cleaning & janitorial industry. It can be used for self-assessments, team audits, and regulatory compliance documentation.

Can I download this checklist as a PDF?

Yes, this checklist is available as a free PDF download. You can also use it digitally in the POPProbe mobile app for real-time data capture, photo documentation, and automatic reporting.

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