Endpoint Security Inspection Checklist [FREE PDF]

Endpoint devices represent one of the most common attack vectors in modern cyber threats, making endpoint security inspection a critical operational and compliance requirement under NIST CSF PR.PT-3, ISO 27001:2022 Annex A.8.7, and PCI DSS v4.0 Requirement 5. Regular inspection ensures that antivirus software is current, operating systems are patched, disk encryption is active, and mobile device management (MDM) policies are enforced across all endpoints. Organizations subject to SOC 2 Type II,

  • Industry: Managed IT Services
  • Frequency: Monthly
  • Estimated Time: 30-45 minutes
  • Role: Systems Administrator
  • Total Items: 37
  • Compliance: NIST CSF PR.PT-3 – Endpoint Protection, ISO 27001:2022 Annex A.8.7 – Protection Against Malware, PCI DSS v4.0 Requirement 5 – Protect All Systems Against Malware, SOC 2 Type II CC6.8 – Endpoint and Malware Controls, HIPAA 45 CFR §164.312(a)(2)(iv) – Encryption and Decryption

Antivirus & Anti-Malware Protection

Verify that endpoint protection software is installed, active, up to date, and performing scheduled scans on all devices.

  • Is an approved antivirus or endpoint detection and response (EDR) solution installed on all endpoints in scope?
  • Are antivirus/EDR signature definitions updated within the last 24 hours on all endpoints?
  • Are automatic real-time protection and on-access scanning features enabled on all endpoints?
  • Are scheduled full-system scans configured to run at least weekly on all endpoints?
  • Are malware scan logs and alerts centrally collected in a SIEM or logging platform?
  • How many endpoints had malware detections or quarantine events in the past 30 days?

Patch Management & OS Currency

Confirm that operating systems and critical applications are patched within defined SLAs and that no endpoints are running end-of-life software.

  • Are all endpoints running a currently supported and vendor-maintained operating system version?
  • Have critical and high-severity OS patches been applied within 30 days of vendor release on all endpoints?
  • Is a patch management tool or platform (e.g., WSUS, Intune, Jamf, Automox) used to deploy and track patches centrally?
  • What percentage of endpoints are fully patched with no outstanding critical or high-severity vulnerabilities?
  • Are third-party applications (browsers, PDF readers, Office suites) also included in the patch management scope?

Full-Disk Encryption

Verify that full-disk encryption is enabled on all endpoints, particularly laptops and portable devices that risk physical theft.

  • Is full-disk encryption (e.g., BitLocker, FileVault, VeraCrypt) enabled on 100% of managed laptops and portable endpoints?
  • Are encryption recovery keys stored securely in a centralized key management system (not on the endpoint itself)?
  • Is encryption compliance status reported and monitored centrally via MDM or endpoint management platform?
  • Are desktop workstations in secure, locked, access-controlled areas exempt from mandatory full-disk encryption per policy?
  • How many endpoints were found to have encryption disabled or not configured during this inspection?

Mobile Device Management (MDM) & Endpoint Policy Enforcement

Confirm that all managed endpoints are enrolled in an MDM platform and that security baseline policies are actively enforced.

  • Are all managed laptops, desktops, and mobile devices enrolled in an approved MDM solution (e.g., Microsoft Intune, Jamf, VMware Workspace ONE)?
  • Are MDM compliance policies configured to block non-compliant endpoints from accessing corporate resources?
  • Is the MDM platform configured to enforce screen lock with a PIN or password after a maximum of 5 minutes of inactivity?
  • Is remote wipe capability tested and confirmed functional for all enrolled mobile and portable devices?
  • Are personal (BYOD) devices accessing corporate resources subject to the same MDM and security baseline policies?

Host-Based Firewall & Application Controls

Verify that host-based firewalls are active on all endpoints and that application allow-listing or execution controls are configured.

  • Is the host-based firewall enabled and enforcing the approved corporate policy on all endpoints?
  • Are endpoints prevented from allowing inbound connections from unauthorized or unknown sources by firewall policy?
  • Is application allow-listing or application control software (e.g., AppLocker, Carbon Black) deployed on high-risk endpoints?
  • Are USB and removable media ports disabled or controlled via endpoint policy to prevent unauthorized data exfiltration?
  • Are DNS filtering or web proxy controls enforced on endpoints to block access to known malicious domains?

Vulnerability Scanning & Remediation

Confirm that authenticated vulnerability scans are run regularly against all endpoints and that findings are tracked to remediation.

  • Are authenticated vulnerability scans performed against all endpoints at least monthly?
  • Are critical vulnerabilities (CVSS score 9.0+) identified on endpoints remediated within 15 days of discovery?
  • Is there a formal vulnerability remediation tracking process with assigned owners and target dates for each finding?
  • Are vulnerability scan reports retained for a minimum of 12 months for audit evidence purposes?
  • What is the current count of unresolved critical (CVSS 9.0+) vulnerabilities across all endpoints in scope?

Endpoint Logging & Monitoring

Verify that security-relevant events from all endpoints are logged, forwarded to a central SIEM, and reviewed on a defined schedule.

  • Are security event logs (logon events, process execution, policy changes) enabled and collected from all endpoints?
  • Are endpoint logs forwarded in real time to a centralized SIEM or log aggregation platform?
  • Are SIEM alerting rules configured to trigger on high-risk endpoint events (e.g., mass file deletion, admin account creation, lateral movement)?
  • Are endpoint logs retained for a minimum of 12 months with at least 3 months immediately available for query?
  • Please document any endpoints found to have logging disabled, misconfigured, or not forwarding to the SIEM during this inspection.
  • What is the overall endpoint security posture rating based on this inspection's findings?

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Why Use This Endpoint Security Inspection Checklist [FREE PDF]?

This endpoint security inspection checklist [free pdf] helps managed it services teams maintain compliance and operational excellence. Designed for systems administrator professionals, this checklist covers 37 critical inspection points across 7 sections. Recommended frequency: monthly.

Ensures compliance with NIST CSF PR.PT-3 – Endpoint Protection, ISO 27001:2022 Annex A.8.7 – Protection Against Malware, PCI DSS v4.0 Requirement 5 – Protect All Systems Against Malware, SOC 2 Type II CC6.8 – Endpoint and Malware Controls, HIPAA 45 CFR §164.312(a)(2)(iv) – Encryption and Decryption. Regulatory-aligned for audit readiness and inspection documentation.

Frequently Asked Questions

What does the Endpoint Security Inspection Checklist [FREE PDF] cover?

This checklist covers 37 inspection items across 7 sections: Antivirus & Anti-Malware Protection, Patch Management & OS Currency, Full-Disk Encryption, Mobile Device Management (MDM) & Endpoint Policy Enforcement, Host-Based Firewall & Application Controls, Vulnerability Scanning & Remediation, Endpoint Logging & Monitoring. It is designed for managed it services operations and compliance.

How often should this checklist be completed?

This checklist should be completed monthly. Each completion takes approximately 30-45 minutes.

Who should use this Endpoint Security Inspection Checklist [FREE PDF]?

This checklist is designed for Systems Administrator professionals in the managed it services industry. It can be used for self-assessments, team audits, and regulatory compliance documentation.

Can I download this checklist as a PDF?

Yes, this checklist is available as a free PDF download. You can also use it digitally in the POPProbe mobile app for real-time data capture, photo documentation, and automatic reporting.

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