Cannabis Distillation and Purification Operations Checklist
This cannabis distillation and purification operations checklist ensures compliance with state cannabis processor license requirements, GMP standards for cannabinoid distillation (short-path and wiped-film), safe vacuum system operation, and METRC batch processing documentation. Distillation is a critical step in producing pharmaceutical-grade cannabinoid distillate with consistent potency above 90% THC or CBD.
- Industry: Cannabis
- Frequency: Per Production Run
- Estimated Time: 30-45 minutes
- Role: Distillation Technician / Lab Manager
- Total Items: 30
- Compliance: State Cannabis Processor License Requirements, OSHA 29 CFR 1910.106 Flammable Liquids (ethanol as carrier), ASME B31.3 Process Piping for Vacuum Systems, METRC Processing Batch Recording Requirements, State Cannabis Concentrate Potency Testing Standards
Feed Material
Input material for distillation.
- COA for crude extract input on file with residual solvent results?
- Feed material weight recorded before loading?
- Winterization and filtration completed on feed material if required?
- Decarboxylation completed on feed material if producing THC distillate?
- Feed material viscosity appropriate for distillation equipment specifications?
Equipment Setup
Pre-run equipment check.
- All glassware inspected for cracks, chips, or seal failures before use?
- Vacuum pump oil level and quality checked?
- Target vacuum (typically below 0.05 mbar) achieved before heating?
- Cooling water circulation operational and at target temperature?
- Heating mantle or heating jacket at correct temperature setting for fraction?
Distillation Process
Run monitoring.
- Distillation fractions (heads, main body, tails) collected separately?
- Flask/feed temperature, vapor temperature, and vacuum logged throughout run?
- No excessive bumping or spattering observed (controlled vacuum maintained)?
- Distillate color and clarity meeting quality specifications?
- Cold trap emptied and waste solvent disposed of properly between runs?
Output Tracking
Yield and METRC.
- All fraction weights recorded (heads, main body, tails, residue)?
- Distillate yield calculated as percentage of feed material?
- METRC processing batch updated with input and all output fractions?
- Potency test sample pulled and submitted to state-licensed lab?
- Non-distillate fractions (heads, tails, residue) properly handled per state rules?
Safety Controls
Distillation safety.
- Heat-resistant gloves and safety glasses worn when handling hot glassware?
- Solvent vapors controlled by local exhaust ventilation?
- No unattended distillation runs when vacuum and heat are active?
- Fire extinguisher accessible within 25 feet of distillation area?
- Emergency shutdown procedure posted and operator trained?
Distillation Records
Documentation.
- Distillation run log completed with all parameters, weights, and observations?
- Equipment cleaning log entry made after run completion?
- Potency COA filed with batch record upon receipt?
- Yield data logged for trending analysis to detect equipment degradation?
- Distillation Notes
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Why Use This Cannabis Distillation and Purification Operations Checklist?
This cannabis distillation and purification operations checklist helps cannabis teams maintain compliance and operational excellence. Designed for distillation technician / lab manager professionals, this checklist covers 30 critical inspection points across 6 sections. Recommended frequency: per production run.
Ensures compliance with State Cannabis Processor License Requirements, OSHA 29 CFR 1910.106 Flammable Liquids (ethanol as carrier), ASME B31.3 Process Piping for Vacuum Systems, METRC Processing Batch Recording Requirements, State Cannabis Concentrate Potency Testing Standards. Regulatory-aligned for audit readiness and inspection documentation.
Frequently Asked Questions
What does the Cannabis Distillation and Purification Operations Checklist cover?
This checklist covers 30 inspection items across 6 sections: Feed Material, Equipment Setup, Distillation Process, Output Tracking, Safety Controls, Distillation Records. It is designed for cannabis operations and compliance.
How often should this checklist be completed?
This checklist should be completed per production run. Each completion takes approximately 30-45 minutes.
Who should use this Cannabis Distillation and Purification Operations Checklist?
This checklist is designed for Distillation Technician / Lab Manager professionals in the cannabis industry. It can be used for self-assessments, team audits, and regulatory compliance documentation.
Can I download this checklist as a PDF?
Yes, this checklist is available as a free PDF download. You can also use it digitally in the POPProbe mobile app for real-time data capture, photo documentation, and automatic reporting.