Cannabis Product Microbial and Potency Sample Preparation Checklist
This cannabis product microbial and potency sample preparation checklist ensures that cannabis testing samples are collected, prepared, and stored using best practices that preserve sample integrity and produce representative, reliable test results. Poor sampling technique is a significant source of misleading test results — particularly for microbial testing where contamination or homogeneity issues can mask true product safety.
- Industry: Cannabis
- Frequency: Per Sample Event
- Estimated Time: 20-30 minutes
- Role: Quality Control Lead / Sampling Technician
- Total Items: 30
- Compliance: State Cannabis Sampling Methodology Requirements, ISO/IEC 17025 Sample Preparation Standards, State Cannabis Minimum Sample Size Requirements, FDA Guidance on Representative Sampling (Adapted), State Cannabis Sample Storage and Stability Requirements
Sample Area Preparation
Preparation before sampling.
- Sampling surface cleaned and sanitized before use?
- All sampling tools sterile or single-use — no cross-batch contamination?
- Fresh sterile or nitrile gloves worn during sampling — changed between product types?
- Appropriate PPE including mask/face covering for microbial sample collection?
- Correctly-sized, labeled sample containers ready before beginning?
Representative Sampling
Ensuring sample represents the batch.
- Samples collected from multiple locations throughout the batch?
- Composite sample created from multiple sub-samples?
- Total sample weight meets state minimum requirement for all panels?
- No selective sampling of best-looking buds — random selection from throughout batch?
- Samples taken from both surface and interior of bulk product when applicable?
Sample Labeling
Sample identification.
- Batch/lot ID written on sample container immediately after collection?
- Collection date and time recorded on sample?
- Product type and strain/flavor on sample container?
- Requested test panels noted with sample for lab processing?
- Unique sample ID assigned matching chain of custody form?
Sample Storage
Pre-shipment storage.
- Microbial samples refrigerated (2-8°C) immediately after collection?
- Potency samples stored away from light and heat until shipment?
- Flower samples NOT frozen (causes cellular changes affecting test results)?
- Samples delivered to lab within recommended stability window (typically 24-48 hours)?
- Microbial and potency samples in separate containers to prevent cross-testing issue?
Source Batch Hold
Quarantine until results received.
- Source batch placed in METRC quarantine after sampling?
- No sales from sampled batch until passing COA received?
- Physical quarantine area labeled 'PENDING TESTING — DO NOT SELL'?
- All relevant staff aware that batch is on testing hold?
- Expected COA return date tracked — follow up with lab if overdue?
Sample Records
Documentation.
- Chain of custody form completed with all required fields?
- Copy of chain of custody form retained at facility?
- Sample submission log updated with batch, lab, panels, and expected return date?
- Photos of sampling process taken for documentation if required or useful?
- Sample Preparation Notes
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Why Use This Cannabis Product Microbial and Potency Sample Preparation Checklist?
This cannabis product microbial and potency sample preparation checklist helps cannabis teams maintain compliance and operational excellence. Designed for quality control lead / sampling technician professionals, this checklist covers 30 critical inspection points across 6 sections. Recommended frequency: per sample event.
Ensures compliance with State Cannabis Sampling Methodology Requirements, ISO/IEC 17025 Sample Preparation Standards, State Cannabis Minimum Sample Size Requirements, FDA Guidance on Representative Sampling (Adapted), State Cannabis Sample Storage and Stability Requirements. Regulatory-aligned for audit readiness and inspection documentation.
Frequently Asked Questions
What does the Cannabis Product Microbial and Potency Sample Preparation Checklist cover?
This checklist covers 30 inspection items across 6 sections: Sample Area Preparation, Representative Sampling, Sample Labeling, Sample Storage, Source Batch Hold, Sample Records. It is designed for cannabis operations and compliance.
How often should this checklist be completed?
This checklist should be completed per sample event. Each completion takes approximately 20-30 minutes.
Who should use this Cannabis Product Microbial and Potency Sample Preparation Checklist?
This checklist is designed for Quality Control Lead / Sampling Technician professionals in the cannabis industry. It can be used for self-assessments, team audits, and regulatory compliance documentation.
Can I download this checklist as a PDF?
Yes, this checklist is available as a free PDF download. You can also use it digitally in the POPProbe mobile app for real-time data capture, photo documentation, and automatic reporting.