Cannabis Concentrate Manufacturing Safety and Compliance Checklist

This cannabis concentrate manufacturing safety and compliance checklist ensures compliance with state cannabis processor license requirements, GMP standards for concentrate production, residual solvent testing requirements, and state cannabis concentrate potency and contaminant action limits. Concentrate manufacturing involves complex multi-step refinement processes each requiring documentation and quality control.

  • Industry: Cannabis
  • Frequency: Per Production Run
  • Estimated Time: 30-45 minutes
  • Role: Lab Manager / Processing Supervisor
  • Total Items: 30
  • Compliance: State Cannabis Processor License Requirements, State Cannabis Concentrate Residual Solvent Testing Standards, OSHA 29 CFR 1910.106 Flammable Liquids, METRC Processing Batch Recording Requirements, State Cannabis Concentrate Potency and Contaminant Action Limits

Input Material Compliance

Starting material verification.

  • COA for input material (flower/trim) on file with passing test results?
  • Input material batch IDs recorded in METRC processing batch?
  • No failed or quarantined material used as input?
  • Input material weighed and recorded before processing?
  • Strain or blend information documented for product labeling?

Process Control

Production step documentation.

  • Approved SOP followed for this concentrate type?
  • Processing temperatures and pressures recorded at each critical step?
  • Winterization temperatures and duration logged if applicable?
  • Distillation temperatures (short-path or wiped-film) logged if applicable?
  • Solvent purge process completed and purge time/temperature documented?

Residual Solvent Compliance

Solvent testing requirements.

  • Residual solvent testing required and ordered for this product type?
  • Residual solvent COA showing PASS for all analytes?
  • Purge process validated to reliably achieve passing residual levels?
  • No Class 1 prohibited solvents (benzene, toluene) used in production?
  • Food-grade or pharmaceutical-grade ethanol used where required?

Yield and METRC Tracking

Production reconciliation.

  • Finished concentrate output weighed and recorded?
  • Yield percentage calculated and within expected range for process?
  • METRC processing batch updated with input and output weights?
  • Processing waste (spent biomass, filtration waste) logged and disposed of correctly?
  • Finished concentrate transfer manifest created before any movement?

Quality and Release

Product quality verification.

  • Visual quality inspection completed (color, consistency, clarity)?
  • Potency COA received and reviewed before product released?
  • All required test panels (potency, residuals, microbials, metals) PASS?
  • Product label potency within state tolerance of COA result?
  • Quality manager sign-off on batch record before release?

Production Records

Batch documentation.

  • Complete batch production record filed with all process data?
  • Equipment maintenance log entries current for all production equipment used?
  • All COAs filed with batch record and accessible for audit?
  • Records retained for state-required minimum period (typically 3-5 years)?
  • Concentrate Production Notes

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Why Use This Cannabis Concentrate Manufacturing Safety and Compliance Checklist?

This cannabis concentrate manufacturing safety and compliance checklist helps cannabis teams maintain compliance and operational excellence. Designed for lab manager / processing supervisor professionals, this checklist covers 30 critical inspection points across 6 sections. Recommended frequency: per production run.

Ensures compliance with State Cannabis Processor License Requirements, State Cannabis Concentrate Residual Solvent Testing Standards, OSHA 29 CFR 1910.106 Flammable Liquids, METRC Processing Batch Recording Requirements, State Cannabis Concentrate Potency and Contaminant Action Limits. Regulatory-aligned for audit readiness and inspection documentation.

Frequently Asked Questions

What does the Cannabis Concentrate Manufacturing Safety and Compliance Checklist cover?

This checklist covers 30 inspection items across 6 sections: Input Material Compliance, Process Control, Residual Solvent Compliance, Yield and METRC Tracking, Quality and Release, Production Records. It is designed for cannabis operations and compliance.

How often should this checklist be completed?

This checklist should be completed per production run. Each completion takes approximately 30-45 minutes.

Who should use this Cannabis Concentrate Manufacturing Safety and Compliance Checklist?

This checklist is designed for Lab Manager / Processing Supervisor professionals in the cannabis industry. It can be used for self-assessments, team audits, and regulatory compliance documentation.

Can I download this checklist as a PDF?

Yes, this checklist is available as a free PDF download. You can also use it digitally in the POPProbe mobile app for real-time data capture, photo documentation, and automatic reporting.

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